Capecitabine Tablets USP 500 mg

You should not take this medication if you are allergic to capecitabine or fluorouracil (Adrucil), or if you have severe kidney disease or a metabolic disorder called DPD (dihydropyrimidine dehydrogenase) deficiency.

Before you take capecitabine, tell your doctor if you have liver or kidney disease, a history of coronary artery disease, or if you are also taking folic acid (contained in many vitamin and mineral supplements), leucovorin (Wellcovorin), phenytoin (Dilantin), or a blood thinner (warfarin, Coumadin).

Call your doctor at once if you have a serious side effect such as:

• nausea, loss of appetite, eating much less than usual, vomiting (more than once in 24 hours)
• severe diarrhea (more than 4 times per day, or during the night)
• bloody, black, or tarry stools
• coughing up blood or vomit that looks like coffee grounds
• fever, chills, body aches, flu symptoms, easy bruising