Cyclophosphamide Injection

Endoxan is a prescription drug. Endoxan should not be used in patients who are pregnant (ADEC Pregnancy Category D) or breastfeeding - always tell your doctor you are pregnant or breast feeding before using Endoxan. Report signs of infection or unusual bleeding to your doctor. Avoid people with infections while undergoing treatment with Endoxan. Drink plenty of fluids and urinate frequently while undergoing treatment with Endoxan. Report any signs of bladder irritation to your doctor.

• Nausea and vomiting
• Appetite loss
• Hair loss - regrowth of hair may be of a different colour or texture
• Nasal congestion (following injection only)
• Delayed wound healing
• Inflammation of the bladder - report bladder irritation or bleeding on urination to your doctor as soon as possible
• Disorders of the blood - report frequent or persistent infections to your doctor, including signs and symptoms of fever, sore throat, unusual bleeding or bruising, and fatigue.
• Infertility - there is a risk of sterility following treatment with Endoxan and this should be discussed with your doctor.

Uncommon side effects:

• The following side effects occur in 0.1 to 1% of patients taking Endoxan:
• Darkening of skin and fingernails.
• Taste disturbances (metallic taste or loss of taste).
• Consult your doctor if you experience any of the above symptoms, or any other unusual or abnormal symptoms that concern you.