Janumet (Sitagliptin/Metformin)

You should not use Janumet (sitagliptin/metformin) if you are allergic to any of its ingredients or if you have type 1 diabetes.  You may need a dose adjustment or special tests to take Janumet (sitagliptin/metformin) safely if you have liver or kidney disease, have a history of pancreatitis or heart disease, or if you are over 80 years old and have not recently had your kidney function checked.  You should make your doctor aware of all your health conditions.  Ensure that your doctor is aware of all prescription, non-prescription and herbal products you are taking when using Janumet to ensure there are no drug interactions.

Low blood sugar (hypoglycemia). If you take JANUMET with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin, your risk of getting low blood sugar is higher. The dose of your sulfonylurea medicine or insulin may need to be lowered while you use JANUMET. Signs and symptoms of low blood sugar may include:

• headache
• drowsiness
• weakness
• dizziness
• confusion
• irritability
• hunger
• fast heart beat
• sweating
• feeling jittery

Serious allergic reactions. If you have any symptoms of a serious allergic reaction, stop taking JANUMET and call your doctor right away. See "Who should not take JANUMET?". Your doctor may give you a medicine for your allergic reaction and prescribe a different medicine for your diabetes.

Kidney problems, sometimes requiring dialysis.

The most common side effects of JANUMET include:

• stuffy or runny nose and sore throat
• upper respiratory infection
• diarrhea
• nausea and vomiting
• gas, upset stomach, indigestion
• weakness
• headache