M-Vac (Measles Vaccine)

INDICATION:
M-VAC is indicated for immunisation of all susceptible children against measles. It is recommended to be given to children at 9 months of age, or as soon as thereafter, to protect against measles in early life. Immunisation against measles is particularly important for institutionalized children and for children who may be malnourished or subject to chronic diseases such as heart disease, cystic fibrosis, asthma, tuberculosis or other chronic pulmonary disorders.

USE:
Reconstitute the freeze dried vaccine by adding the entire contents of the diluent (Sterile Water for Injections) supplied to the single-dose vial by using sterile disposable syringe and needle. With gentle shaking the dried cake is easily dissolved. After reconstitution the vaccine should be used immediately. A
single dose of 0.5 ml should be administered by deep subcutaneous injection into the upper arm.
The diluent and reconstituted vaccine should be inspected visually for any foreign particulate matter and / or variation of physical aspects prior to administration. In the event of either being observed, discard the diluent or reconstituted vaccine.
The reconstituted vaccine must be used immediately otherwise it should be discarded.

CONTRAINDICATIONS:

1. Febrile state,
2. Acute infectious diseases,
3. Severe diseases of the hematopoietic system,
4. Severe impairment of the renal function,
5. Decompensated heart diseases,
6. States of reduced immunity, either congenital or therapeutically acquired through  irradiation and use of corticosteroid or cytostatic drugs,
7. States of reduced immunity, following the transplantation of an organ,
8. Diseases and disorders of the central nervous system,
9. Within three months following the administration of gammaglobulin or blood-transfusion,
10. Within six months following exchange transfusion,
11. Pregnancy.

STORAGE:
M-VAC should be stored between +2°C and +8°C. Protect from light. Diluent should not be frozen and should be stored in a clean place away from heat and sunlight.

PRESENTATION:
Sii Measles Vaccine (M-VACT) is presented as freeze-dried vaccine
1 Dose x 10 vials plus diluent (0.5ml Sterile Water for Injections I.P.) and sterile disposable syringe and needle supplied separately.

Some mild reactions may occur such as marginal temperature rise in 5% to 6% of the vaccinated children, mild rash in 1% to 2% children, occasionally mild rash and slight gastric disorders or short-lived rhinopharyngitis. Fever or rash, or both, generally appear between the 5th and the 12th day after vaccination and last for one to two days.